Attenuation of high sweet solution preference by mood stabilizers: A possible mouse model for the increased reward-seeking domain of mania

@article{FlaisherGrinberg2009AttenuationOH,
  title={Attenuation of high sweet solution preference by mood stabilizers: A possible mouse model for the increased reward-seeking domain of mania},
  author={Shlomit Flaisher-Grinberg and Shauna M. Overgaard and Haim Einat},
  journal={Journal of Neuroscience Methods},
  year={2009},
  volume={177},
  pages={44-50}
}
The lack of appropriate animal models for bipolar disorder (BPD) is a major factor hindering the research of its pathophysiology and the development of new drug treatments. In line with the notion that BPD might represent a heterogeneous group of disorders, it was suggested that models for specific domains of BPD should be developed and then integrated. The present study tested sweet solution preference as a rodent model for increased reward seeking, a central component of manic behavior and a… CONTINUE READING
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