Attenuation of high-glucose-induced inflammatory response by a novel curcumin derivative B06 contributes to its protection from diabetic pathogenic changes in rat kidney and heart.

@article{Pan2013AttenuationOH,
  title={Attenuation of high-glucose-induced inflammatory response by a novel curcumin derivative B06 contributes to its protection from diabetic pathogenic changes in rat kidney and heart.},
  author={Yong Pan and Guanghui Zhu and Yi Wang and Lu Cai and Yuepiao Cai and Jie Hu and Yilan Li and Yongbo Yan and Zengshou Wang and Xiaokun Li and Tie-min Wei and Guang Liang},
  journal={The Journal of nutritional biochemistry},
  year={2013},
  volume={24 1},
  pages={146-55}
}
There is increasing evidence indicating that inflammatory processes are involved in the development and progression of diabetic complications. However, effective anti-inflammatory treatments for patients who have diabetic complications have yet been practically identified. Curcumin is a main component of Curcuma longa with numerous pharmacological activities. Previously, we synthesized a novel curcumin analogue (B06) that exhibited an improved pharmacokinetic and enhanced anti-inflammatory… CONTINUE READING

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