Attenuation of high cholesterol-induced oxidative stress in rabbit liver by thymoquinone.

  title={Attenuation of high cholesterol-induced oxidative stress in rabbit liver by thymoquinone.},
  author={Ahmed Hamed Attia and Ahmed Ragheb and Thomas Sylwestrowicz and Ahmed Shoker},
  journal={European journal of gastroenterology & hepatology},
  volume={22 7},
BACKGROUND/AIMS This study examines the modifying effects of thymoquinone (TQ), an agent with antioxidant and hypolipidemic properties, on reactive oxygen species, antioxidant activity, and steatosis in livers of hyperlipidemic rabbit. METHODS Oxidative stress was induced in New Zealand White rabbit by a high-cholesterol diet for 8 weeks. Four groups of six animals each were divided into a control group; a high cholesterol group (received 1% cholesterol diet); a high cholesterol/low TQ group… CONTINUE READING
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