Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis

@article{Philpott2017AttenuationOE,
  title={Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis},
  author={H. T. Philpott and M. O’Brien and J. McDougall},
  journal={Pain},
  year={2017},
  volume={158},
  pages={2442 - 2451}
}
Abstract Osteoarthritis (OA) is a multifactorial joint disease, which includes joint degeneration, intermittent inflammation, and peripheral neuropathy. Cannabidiol (CBD) is a noneuphoria producing constituent of cannabis that has the potential to relieve pain. The aim of this study was to determine whether CBD is anti-nociceptive in OA, and whether inhibition of inflammation by CBD could prevent the development of OA pain and joint neuropathy. Osteoarthritis was induced in male Wistar rats… Expand

Paper Mentions

Interventional Clinical Trial
This randomized, double-blind 2-arm parallel group study to determine the efficacy of a cannabinoid (CBD) patch on reducing pain in patients with knee osteoarthritis.  
ConditionsCBD, Knee Osteoarthritis, Osteoarthritis
InterventionDrug, Other
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