Attenuation of alcohol intake by Ibogaine in three strains of alcohol-preferring rats

@article{Rezvani1995AttenuationOA,
  title={Attenuation of alcohol intake by Ibogaine in three strains of alcohol-preferring rats},
  author={Amir H. Rezvani and David H. Overstreet and Yue-Wei Leef},
  journal={Pharmacology Biochemistry and Behavior},
  year={1995},
  volume={52},
  pages={615-620}
}
Alcohol-preferring (P), Fawn-Hooded (FH) and alcohol-accepting (AA) rats were injected intraperitoneally (IP) or subcutaneously (SC) with different doses (10, 30, and 60 mg/kg) of Ibogaine or vehicle. In a separate experiment, FH rats were administered intragastrically (IG) with either 60 mg/kg of Ibogaine or vehicle for 5 days. In addition, the effects of Ibogaine on blood alcohol concentrations were measured. Our data show that, contrary to the SC administration of Ibogaine, IP administration… Expand
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