Attenuation by cyclic phosphatidic acid of peritoneal metastasis of azoxymethane‐induced intestinal cancers in Wistar rats

@article{Ishihara2004AttenuationBC,
  title={Attenuation by cyclic phosphatidic acid of peritoneal metastasis of azoxymethane‐induced intestinal cancers in Wistar rats},
  author={R. Ishihara and M. Tatsuta and H. Iishi and M. Baba and N. Uedo and K. Higashino and M. Mukai and S. Ishiguro and Susumu Kobayashi and K. Murakami‐Murofushi},
  journal={International Journal of Cancer},
  year={2004},
  volume={110}
}
The effect of cyclic phosphatidic acid, a unique analogue of lysophosphatidic acid, on the induction of bombesin‐enhanced peritoneal metastases from intestinal adenocarcinomas induced by azoxymethane was investigated in male Wistar rats. Rats were given 10 weekly injections of azoxymethane (7.4 mg/kg body weight, s.c.) and of bombesin (40 μg/kg body weight, s.c.) every other day from the start of the experiment, and from week 16, they received injections of cyclic phosphatidic acid (3 or 6 mg… Expand
Cyclic phosphatidic acid - a unique bioactive phospholipid.
  • Y. Fujiwara
  • Biology, Medicine
  • Biochimica et biophysica acta
  • 2008
Biologic activity of cyclic and caged phosphates: a review
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