Attenuated sympathetic nerve responses after 24 hours of bed rest.

  title={Attenuated sympathetic nerve responses after 24 hours of bed rest.},
  author={M Saddam Hossain Khan and Allen R Kunselman and Urs A. Leuenberger and William R. Davidson and Chester A. Ray and Kristen S. Gray and Cynthia S Hogeman and Lawrence I. Sinoway},
  journal={American journal of physiology. Heart and circulatory physiology},
  volume={282 6},
Bed rest reduces orthostatic tolerance. Despite decades of study, the cause of this phenomenon remains unclear. In this report we examined hemodynamic and sympathetic nerve responses to graded lower body negative pressure (LBNP) before and after 24 h of bed rest. LBNP allows for baroreceptor disengagement in a graded fashion. We measured heart rate (HR), cardiac output (HR x stroke volume obtained by echo Doppler), and muscle sympathetic nerve activity (MSNA) during a progressive and graded… CONTINUE READING


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The Echo Manual (2nd ed.)

JK Oh, JB Seward, AJ. Tajik
Philadelphia, PA: Lippincott-Raven, • 1999
View 1 Excerpt

Changes in the sympathetic nervous system induced by 42 days of head-down bed rest.

American journal of physiology. Heart and circulatory physiology • 1998
View 1 Excerpt

Orthostatic intolerance after spaceflight.

Journal of applied physiology • 1996
View 1 Excerpt

SAS System for Mixed Models

RC Littell, GA Milliken, WW Stroup, RD. Wolfinger
Cary, NC: SAS Institute, • 1996
View 2 Excerpts

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