Attenuated store-operated Ca2+ entry underpins the dual inhibition of nitric oxide and EDHF-type relaxations by iodinated contrast media.

Abstract

AIMS Our objective was to investigate whether alterations in endothelial Ca(2+) homeostasis contribute to the clinical toxicity of iodinated radiographic contrast media (IRCM) by modulating nitric oxide (NO) production and the endothelium-derived hyperpolarizing factor (EDHF) phenomenon. METHODS AND RESULTS The triiodinated monomer iohexol caused… (More)
DOI: 10.1093/cvr/cvp239

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Cite this paper

@article{FernandezRodriguez2009AttenuatedSC, title={Attenuated store-operated Ca2+ entry underpins the dual inhibition of nitric oxide and EDHF-type relaxations by iodinated contrast media.}, author={Sofia Fernandez-Rodriguez and David H. Edwards and Ben Newton and Tudor M. Griffith}, journal={Cardiovascular research}, year={2009}, volume={84 3}, pages={470-8} }