Attenuated portal hypertension in germ-free mice: Function of bacterial flora on the development of mesenteric lymphatic and blood vessels.

@article{Moghadamrad2015AttenuatedPH,
  title={Attenuated portal hypertension in germ-free mice: Function of bacterial flora on the development of mesenteric lymphatic and blood vessels.},
  author={Sheida Moghadamrad and Kathy D McCoy and Markus B Geuking and Hans Saegesser and Jorum K Kirundi and Andrew J Macpherson and Andrea de Gottardi},
  journal={Hepatology},
  year={2015},
  volume={61 5},
  pages={1685-95}
}
UNLABELLED Intestinal bacterial flora may induce splanchnic hemodynamic and histological alterations that are associated with portal hypertension (PH). We hypothesized that experimental PH would be attenuated in the complete absence of intestinal bacteria. We induced prehepatic PH by partial portal vein ligation (PPVL) in germ-free (GF) or mice colonized with altered Schaedler's flora (ASF). After 2 or 7 days, we performed hemodynamic measurements, including portal pressure (PP) and… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 36 references

Similar Papers

Loading similar papers…