Attenuated development of renal hypertension in essential fatty acid-deficient rats.

@article{Nijkamp1983AttenuatedDO,
  title={Attenuated development of renal hypertension in essential fatty acid-deficient rats.},
  author={Frans P. Nijkamp and Wybren De Jong},
  journal={Archives internationales de pharmacodynamie et de therapie},
  year={1983},
  volume={265 1},
  pages={103-14}
}
Renal hypertension (one-clip, two kidney) developed to a lower level in essential fatty acid (EFA)-deficient rats than in controls on a complete diet. Body weight gain was the same in both clipped groups. Hypertension in rats on an EFA-deficient diet supplemented with linoleic acid (corn oil) was comparable to that in rats on a complete diet. Plasma renin activity was significantly higher in both hypertensive groups. However, in the EFA-deficient groups the difference between hypertensive and… CONTINUE READING