Attenuated brain-derived neurotrophic factor and hypertrophic remodelling: the SABPA study

@article{Smith2015AttenuatedBN,
  title={Attenuated brain-derived neurotrophic factor and hypertrophic remodelling: the SABPA study},
  author={Anthony J Tony Smith and Leon{\'e} Malan and Aletta S Uys and Nicolaas Theodore Malan and Brian Herbert Harvey and Tjalf Ziemssen},
  journal={Journal of Human Hypertension},
  year={2015},
  volume={29},
  pages={33-39}
}
Brain-derived neurotrophic factor (BDNF) has been linked to neurological pathologies, but its role in cardiometabolic disturbances is limited. We aimed to assess the association between serum BDNF levels and structural endothelial dysfunction (ED) as determined by cross-sectional wall area (CSWA) and albumin/creatinine ratio (ACR) in black Africans. Ambulatory blood pressure (BP) and ultrasound CSWA values were obtained from 82 males and 90 females. Fasting blood and 8 h overnight urine samples… CONTINUE READING

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