Attention-deficit hyperactivity disorder and the gene for the dopamine D5 receptor

@article{Barr2000AttentiondeficitHD,
  title={Attention-deficit hyperactivity disorder and the gene for the dopamine D5 receptor},
  author={Cathy L. Barr and Karen G Wigg and Yu Feng and Gwyneth C M Zai and Molly M. Malone and Wendy Roberts and Russell J. Schachar and Rosemary Tannock and James L Kennedy},
  journal={Molecular Psychiatry},
  year={2000},
  volume={5},
  pages={548-551}
}
A recent study has suggested a possible association of a polymorphism near the dopamine D5 receptor gene (DRD5) and attention-deficit hyperactivity disorder.1 The polymorphism studied was a (CA)n repeat located in the cosmid containing the D5 receptor gene2 and the allele that was reported to be associated with attention-deficit hyperactivity disorder (ADHD) was the 148-bp allele. In this study we sought to replicate this finding by testing for biased transmission of the alleles at this same… CONTINUE READING
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dopamine receptor missense and nonsense variants: differences in dopamine binding affinities

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