Attention deficit hyperactivity disorder (ADHD) and the dopamine D4 receptor gene: evidence of association but no linkage in a UK sample

@article{Mill2001AttentionDH,
  title={Attention deficit hyperactivity disorder (ADHD) and the dopamine D4 receptor gene: evidence of association but no linkage in a UK sample},
  author={Jonathan Mill and Sarah Curran and Lindsey Kent and Sandra Richards and A. Lawrence Gould and V Virdee and Louise Huckett and Janice Sharp and Carrie Anne Batten and Sudarshan Fernando and E Simanoff and Margaret Thompson and Jing Hua Zhao and Pak Sham and Eric Taylor and Philip Asherson},
  journal={Molecular Psychiatry},
  year={2001},
  volume={6},
  pages={440-444}
}
Recent studies report association and linkage between attention deficit hyperactivity disorder (ADHD) and the 7-repeat allele of a 48 base-pair repeat in the dopamine D4 receptor gene (DRD4).1 We examined the frequency of this allele in a sample of probands with DSM-IV ADHD using a case-control design, as well as the transmission disequilibrium test (TDT) and haplotype-based haplotype relative risk (HHRR) in the subset of probands with DNA available from both parents. One hundred and thirty-two… CONTINUE READING
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