Attempts to demonstrate indirect T cell allorecognition of donor MHC peptides in transplant patients.

@article{Saleem1996AttemptsTD,
  title={Attempts to demonstrate indirect T cell allorecognition of donor MHC peptides in transplant patients.},
  author={Moin Saleem and Kina Gustafsson and J W Fabre},
  journal={Immunology letters},
  year={1996},
  volume={54 1},
  pages={21-4}
}
Indirect T cell allorecognition has been shown to play an important role in the rejection of allografts in experimental animals. Although there has been much speculation as to its role in clinical transplantation, especially with regard to chronic rejection, indirect T cell allorecognition has been difficult to demonstrate in transplant patients. In this paper, we looked for in vitro T cell proliferation to synthetic peptides corresponding to donor HLA-A and HLA-B incompatible antigens. Twelve… CONTINUE READING

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