Attempt at therapy in sulphite oxidase deficiency

Sulphite oxidase deficiency (McKusick 27230) is an hereditary disorder of sulphur metabolism. The degradative metabolism of cysteine and methionine in normal individuals entails the conversion of sulphur atoms of the amino acids to sulphite which is converted to sulphate by sulphite oxidase, a molybdenum cofactorcontaining enzyme. The biochemical lesion in… CONTINUE READING