Attack frequency and disease duration as indicators for brain damage in migraine.

@article{Schmitz2008AttackFA,
  title={Attack frequency and disease duration as indicators for brain damage in migraine.},
  author={Nicole Schmitz and Faiza Admiraal-Behloul and Enrico b Arkink and Mark C. Kruit and Guus Geurt Schoonman and Michel D. Ferrari and Mark A. van Buchem},
  journal={Headache},
  year={2008},
  volume={48 7},
  pages={1044-55}
}
OBJECTIVE The aim of this study was to pinpoint predilection sites of brain damage in migraine by quantitatively identifying morphometric and diffusion differences in migraineurs, compared with control subjects, and to assess whether migraine attack frequency and attack history are indicators for brain abnormalities in migraineurs. BACKGROUND Previous clinical neuroimaging investigations introduced the concept of migraine as a progressive brain disease. They reported an increased risk of… CONTINUE READING