Attachment of Fusobacterium nucleatum PK1594 to mammalian cells and its coaggregation with periodontopathogenic bacteria are mediated by the same galactose-binding adhesin.

@article{Weiss2000AttachmentOF,
  title={Attachment of Fusobacterium nucleatum PK1594 to mammalian cells and its coaggregation with periodontopathogenic bacteria are mediated by the same galactose-binding adhesin.},
  author={Ervin Itzhak Weiss and B Shaniztki and Miri Dotan and N. Ganeshkumar and Paul E. Kolenbrander and Zvi Metzger},
  journal={Oral microbiology and immunology},
  year={2000},
  volume={15 6},
  pages={371-7}
}
It has been shown that Fusobacterium nucleatum PK1594 coaggregates with Prophyromonas gingivalis PK1924 through a galactose-binding adhesin. In the present study, attachment of F. nucleatum PK1594 to a variety of mammalian cells was characterized. F. nucleatum PK1594 attached to all eukaryotic cells tested, including human buccal epithelial cells, gingival and periodontal ligament fibroblasts, HeLa cells and murine lymphocytes, macrophages, and polymorphonuclear leukocytes. These attachments… CONTINUE READING

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