Attachment and growth of cultured fibroblast cells on PVA/chitosan-blended hydrogels.

  title={Attachment and growth of cultured fibroblast cells on PVA/chitosan-blended hydrogels.},
  author={Takashi Koyano and Norihiko Minoura and Michiaki Nagura and Kenji Kobayashi},
  journal={Journal of biomedical materials research},
  volume={39 3},
Hydrogels were prepared from poly(vinyl alcohol) and chitosan in various blend ratios. The water contents of the hydrogels were in the range of 65 to 75 wt %. The attachment and growth of fibroblast cells (L-929) on the hydrogels were studied with a cell culture method. On the hydrogels with more than 15 wt % chitosan content, the attached cells were able not only to remain viable but also to proliferate. The relative cell attachment after incubation for 30 h increased with increasing chitosan… CONTINUE READING
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