Atrophy responses to muscle inactivity. II. Molecular markers of protein deficits.

@article{Haddad2003AtrophyRT,
  title={Atrophy responses to muscle inactivity. II. Molecular markers of protein deficits.},
  author={Fadia Haddad and Roland R. Roy and Hui Zhong and V. Reggie Edgerton and Kenneth M. Baldwin},
  journal={Journal of applied physiology},
  year={2003},
  volume={95 2},
  pages={
          791-802
        }
}
We examined the expression of several molecular markers of protein balance in response to skeletal muscle atrophy induced by spinal cord isolation (SI; i.e., a complete transection of the spinal cord at both a midthoracic and a high sacral level plus complete deafferentation between the two transection sites). This treatment nearly eliminates neuromuscular activity (activation and loading) of the hindlimb muscles while maintaining neuromuscular connectivity. SI was associated with a reduced… 

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