Atrophy of large myelinated motor axons and declining muscle grip strength following mercury vapor inhalation in mice.

@article{Stankovic2006AtrophyOL,
  title={Atrophy of large myelinated motor axons and declining muscle grip strength following mercury vapor inhalation in mice.},
  author={Roger Kevin Stankovic},
  journal={Inhalation toxicology},
  year={2006},
  volume={18 1},
  pages={57-69}
}
The effects of acute mercury vapor (Hg(0)) exposure on the peripheral motor system have not been previously addressed in the literature. Early case studies report that acute exposure in humans can cause symptoms resembling motor neuron disease (MND). Mercury granules can be histochemically demonstrated in the cytoplasm of murine motor neurons following Hg(0) exposure, suggesting it is transported from the neuromuscular junction (NMJ) to the cell body by retrograde axonal transport mechanisms… CONTINUE READING

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