Atrophy and structural variability of the upper cervical cord in early multiple sclerosis.

@article{Biberacher2015AtrophyAS,
  title={Atrophy and structural variability of the upper cervical cord in early multiple sclerosis.},
  author={Viola Biberacher and Christine C. Boucard and Paul Schmidt and Christina Engl and Dorothea Buck and Achim Berthele and Muna-Miriam Hoshi and C Zimmer and Bernhard Hemmer and Mark M{\"u}hlau},
  journal={Multiple sclerosis},
  year={2015},
  volume={21 7},
  pages={875-84}
}
BACKGROUND Despite agreement about spinal cord atrophy in progressive forms of multiple sclerosis (MS), data on clinically isolated syndrome (CIS) and relapsing-remitting MS (RRMS) are conflicting. OBJECTIVE To determine the onset of spinal cord atrophy in the disease course of MS. METHODS Structural brain magnetic resonance imaging (MRI) was acquired from 267 patients with CIS (85) or RRMS (182) and 64 healthy controls (HCs). The upper cervical cord cross-sectional area (UCCA) was… CONTINUE READING
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