Atrium as a source of brain natriuretic polypeptide in patients with atrial fibrillation.

@article{Inoue2000AtriumAA,
  title={Atrium as a source of brain natriuretic polypeptide in patients with atrial fibrillation.},
  author={Sanae Inoue and Yoshimasa Murakami and Keita Sano and Harumi Katoh and Toshio Shimada},
  journal={Journal of cardiac failure},
  year={2000},
  volume={6 2},
  pages={92-6}
}
BACKGROUND Plasma brain natriuretic polypeptide (BNP) levels have been used as biochemical markers of systolic left ventricular (LV) dysfunction. Although in vitro studies have shown the existence of BNP messenger RNA in the atria, the main production site of BNP is believed to be the ventricle. The hypothesis that the atrium could be a source of BNP was examined in patients with lone atrial fibrillation (AF), the most common type of sustained arrhythmia. METHODS AND RESULTS We studied 16… CONTINUE READING

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