Atrioventricular valve development: new perspectives on an old theme.


Atrioventricular valve development commences with an EMT event whereby endocardial cells transform into mesenchyme. The molecular events that induce this phenotypic change are well understood and include many growth factors, signaling components, and transcription factors. Besides their clear importance in valve development, the role of these transformed… (More)
DOI: 10.1016/j.diff.2012.04.001