Atrial septal defect repair after a 10-month treatment with bosentan in a patient with severe pulmonary arterial hypertension: a case report.

@article{Hoetzenecker2009AtrialSD,
  title={Atrial septal defect repair after a 10-month treatment with bosentan in a patient with severe pulmonary arterial hypertension: a case report.},
  author={Konrad Hoetzenecker and Hendrik Jan Ankersmit and Diana Bonderman and Wolfram Hoetzenecker and Reinald Seitelberger and Walter Klepetko and Irene M Lang},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={2009},
  volume={137 3},
  pages={760-1}
}
Congenital type II atrial septal defect (ASD) is associated with precapillary pulmonary hypertension (PAH) in roughly 10% of cases. Principally, closure of the shunt lesion is recommended, and large ASDs must be repaired in early childhood to prevent Eisenmenger’s syndrome. Once severe pulmonary hypertension or Eisenmenger’s syndrome has developed, ASD… CONTINUE READING