Atrial natriuretic peptide vascular receptor: regulation of low-affinity binding by calcium.

@article{Morton1989AtrialNP,
  title={Atrial natriuretic peptide vascular receptor: regulation of low-affinity binding by calcium.},
  author={James J. Morton and E C Beattie and Fiona Lyall},
  journal={Clinical science},
  year={1989},
  volume={76 1},
  pages={9-11}
}
1. In the presence of calcium, both high- [dissociation equilibrium constant (Kd) 5.8 x 10(-11) mol/l] and low- (Kd 1.2 x 10(-8) mol/l) affinity binding of atrial natriuretic peptide was detected on plasma membranes prepared from sodium-depleted rats. 2. In contrast, under calcium-free conditions only high-affinity binding (Kd 6.9 x 10(-11) mol/l) was… CONTINUE READING