Atrial natriuretic peptide induces breakdown of phosphatidylinositol phosphates in cultured vascular smooth-muscle cells.

@article{Resink1988AtrialNP,
  title={Atrial natriuretic peptide induces breakdown of phosphatidylinositol phosphates in cultured vascular smooth-muscle cells.},
  author={Th{\'e}rese J. Resink and Timothy Scott-Burden and Ulrich Baur and Chris R. Jones and Fritz R. B{\"u}hler},
  journal={European journal of biochemistry},
  year={1988},
  volume={172 2},
  pages={499-505}
}
Discrepancies exist between extent of guanylate cyclase activation by atrial natriuretic peptide (ANP) in cell-free systems and ANP-stimulated levels of cyclic GMP in whole cells, and also between receptor affinity and dose effectiveness of ANP. Therefore, we have investigated whether, in addition to receptor-coupled guanylate cyclase activation, other… CONTINUE READING