Atrial natriuretic peptide gene transfection with a novel envelope vector system ameliorates pulmonary hypertension in rats.

Abstract

OBJECTIVES A novel hemagglutinating virus of Japan (HVJ, a murine parainfluenza virus) envelope vector system, in which DNA is incorporated into an inactivated viral particle deprived of its genome, was recently developed as a ready-to-use vector for gene therapy. We therefore investigated whether intratracheal gene transfer using this vector can induce… (More)
DOI: 10.1016/j.jtcvs.2007.10.061

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@article{Mitani2008AtrialNP, title={Atrial natriuretic peptide gene transfection with a novel envelope vector system ameliorates pulmonary hypertension in rats.}, author={Yoshihide Mitani and Junko Maruyama and Bao Hua Jiang and Hirofumi Sawada and Hideto Shimpo and Kyoko Imanaka-Yoshida and Yasufumi Kaneda and Yoshihiro Komada and Kazuo Maruyama}, journal={The Journal of thoracic and cardiovascular surgery}, year={2008}, volume={136 1}, pages={142-9} }