Atrial natriuretic factor. Is it physiologically important?

@article{Burnett1990AtrialNF,
  title={Atrial natriuretic factor. Is it physiologically important?},
  author={John C. Burnett},
  journal={Circulation},
  year={1990},
  volume={82 4},
  pages={1523-4}
}
T he heart as an endocrine gland was unequivocally established with the ingenious experiments of DeBold and coworkers 1981 that demonstrated the existence of atrial natriuretic factor (ANF).1 These and subsequent studies have reported that ANF exists as a prepro-ANF molecule that is stored as a 126-amino-acid pro-ANF within atrial granules.2,3 In response… CONTINUE READING