Atrial natriuretic factor (ANF) and ANF receptor C gene expression and localization in the respiratory system: effects induced by hypoxia and hemodynamic overload.

@article{Nardo1996AtrialNF,
  title={Atrial natriuretic factor (ANF) and ANF receptor C gene expression and localization in the respiratory system: effects induced by hypoxia and hemodynamic overload.},
  author={Paolo Di Nardo and M. Minieri and Maurilio Sampaolesi and Arnaldo Carbone and Fabrizio Loreni and Jane Lise Samuel and Renato Lauro},
  journal={Endocrinology},
  year={1996},
  volume={137 10},
  pages={4339-50}
}
Atrial natriuretic factor (ANF) and ANF receptor C (ANF.RC) expression have been investigated in healthy and cardiomyopathic hamsters (CMPH) with widespread necrosis of the diaphragm and myocardium leading to respiratory and heart failure. ANF- and ANF.RC-producing cells were localized in different structures of the respiratory system, and the regulation of their expression by the individual and/or combined action of hypoxia and hemodynamic overload was analyzed. The study was performed in 20… CONTINUE READING