Atrial fibrillation begets atrial fibrillation: autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing.

@article{Lu2008AtrialFB,
  title={Atrial fibrillation begets atrial fibrillation: autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing.},
  author={Zhibing Lu and Benjamin J. Scherlag and Jiaxiong Lin and Guodong Niu and K M Fung and Lichao Zhao and Muhammad Ghias and Warren M. Jackman and Ralph Lazzara and Hong Jiang and Sunny S. Po},
  journal={Circulation. Arrhythmia and electrophysiology},
  year={2008},
  volume={1 3},
  pages={184-92}
}
BACKGROUND The mechanism(s) for acute changes in electrophysiological properties of the atria during rapid pacing induced atrial fibrillation (AF) is not completely understood. We sought to evaluate the contribution of the intrinsic cardiac autonomic nervous system in acute atrial electrical remodeling and AF induced by 6-hour rapid atrial pacing. METHODS AND RESULTS Continuous rapid pacing (1200 bpm, 2x threshold [TH]) was performed at the left atrial appendage. Group 1 (n=7) underwent 6… CONTINUE READING
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