Atrial fibrillation ablation patients have long-term stroke rates similar to patients without atrial fibrillation regardless of CHADS2 score.

@article{Bunch2013AtrialFA,
  title={Atrial fibrillation ablation patients have long-term stroke rates similar to patients without atrial fibrillation regardless of CHADS2 score.},
  author={Thomas Jared Bunch and Heidi T. May and Tami L Bair and J. Peter Weiss and Brian G. Crandall and Jeffrey S. Osborn and Charles Mallender and Jeffrey L. Anderson and Brent Muhlestein and Donald L. Lapp{\'e} and John D. Day},
  journal={Heart rhythm},
  year={2013},
  volume={10 9},
  pages={
          1272-7
        }
}
BACKGROUND Atrial fibrillation (AF) is a leading cause of total and fatal ischemic stroke. Stroke risk after AF ablation appears to be favorably affected; however, it is largely unknown whether the benefit extends to all stroke CHADS2 risk profiles of AF patients. OBJECTIVE To determine if ablation of atrial fibrillation reduces stroke rates in all risk groups. METHODS A total of 4212 consecutive patients who underwent AF ablation were compared (1:4) with 16,848 age-/sex-matched controls… Expand
Risk of stroke after catheter ablation versus cardioversion for atrial fibrillation: A propensity-matched study of 24,244 patients.
TLDR
In patients with AF, there is a small periprocedural stroke risk with ablation in comparison to cardioversion, however, over longer-term follow-up, ablation is associated with a slightly lower rate of stroke. Expand
Stroke rates before and after ablation of atrial fibrillation and in propensity-matched controls in the UK
TLDR
Results suggest the divergence in outcome rates stems from variance in the treatment pathways beginning at the index date, which is significantly lower yearly event rates in the ablation cohort. Expand
Adverse Clinical Events during Long-Term Follow-Up After Catheter Ablation of Atrial Fibrillation.
TLDR
Anticoagulants were discontinued in nearly half the patients who underwent AF ablation; of these, 39.1% experienced AF recurrences, 1.95% suffered from strokes, and 0.98% died, but the risk of death afterAF ablation appeared to be lower than that in a propensity score-matched control group without ablation during long-term follow-up. Expand
Comparison of Long-Term Adverse Outcomes in Patients With Atrial Fibrillation Having Ablation Versus Antiarrhythmic Medications.
TLDR
In a contemporary, multicenter, propensity-matched observational cohort, AF ablation was not significantly associated with death, intracranial hemorrhage, ischemic stroke or transient isChemic attack, or heart failure hospitalization, but was associated with a higher rate of all cause-hospitalization. Expand
Catheter ablation of atrial fibrillation in patients with heart failure: impact of maintaining sinus rhythm on heart failure status and long-term rates of stroke and death.
  • W. Ullah, L. Ling, +16 authors R. Hunter
  • Medicine
  • Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
  • 2016
TLDR
Long-term success rates for persistent (but not paroxysmal) AF ablation are significantly lower in HF patients, and recurrent arrhythmia strongly predicted stroke and death during follow-up. Expand
Outcomes and Anticoagulation Use After Catheter Ablation for Atrial Fibrillation.
TLDR
In this large US national registry, there was no difference in adjusted rates of cardiovascular or all-cause death between patients treated with AF catheter ablation and antiarrhythmic medications only. Expand
Discontinuing anticoagulation following successful atrial fibrillation ablation in patients with prior strokes
TLDR
Most patients who appear AF free postablation may be able to discontinue OAC after successful ablation with a low thromboembolic risk and with a reduced bleeding risk, and Kaplan–Meier analysis suggests little AF recurrence >1 year following initial or final ablations, suggesting that 1 year post successful ablated may be the appropriate time to consider discontinuing OAC. Expand
Usefulness of Long-Term Anticoagulation After Catheter Ablation of Atrial Fibrillation.
TLDR
There is considerable variation in the long-term management of AC after an ablation, but for the present, it seems prudent to continue AC based on stroke risk scores until more definite data are available. Expand
Incidence of ischemic stroke or transient ischemic attack in patients with multiple risk factors with or without atrial fibrillation: a retrospective cohort study
TLDR
In a large cohort of elderly patients without AF, the risk of ischemic stroke/TIA increased substantially in the presence of multiple RFs, highlighting potentially unmet medical needs. Expand
Mortality and cerebrovascular events after radiofrequency catheter ablation of atrial fibrillation.
TLDR
Investigating whether maintaining sinus rhythm after radiofrequency ablation of AF is associated with an improvement in the risk of cerebrovascular events (CVEs) and mortality during an extended 10-year follow-up found it is linked with a reduction in cardiovascular mortality in patients with AF. Expand
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