Atrial contractile dysfunction after short-term atrial fibrillation is reduced by verapamil but increased by BAY K8644.

@article{Leistad1996AtrialCD,
  title={Atrial contractile dysfunction after short-term atrial fibrillation is reduced by verapamil but increased by BAY K8644.},
  author={Elisabeth Leistad and Gunnar Aksnes and Esther Verburg and Geir Christensen},
  journal={Circulation},
  year={1996},
  volume={93 9},
  pages={1747-54}
}
BACKGROUND Reduced atrial contractility occurs after cessation of atrial fibrillation. Its mechanism is unknown, and no pharmacological treatment exists. It has been hypothesized that this atrial contractile dysfunction results from intracellular calcium overload due to rapid depolarizations during fibrillation. Accordingly, we examined the effects of drugs that reduce or increase transsarcolemmal calcium influx on postfibrillation atrial dysfunction. Furthermore, we examined whether the… CONTINUE READING

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