Atovaquone ameliorate gastrointestinal Toxoplasmosis complications in a pregnancy model

  title={Atovaquone ameliorate gastrointestinal Toxoplasmosis complications in a pregnancy model},
  author={Helieh S Oz and Thomas T Tobin},
  booktitle={Medical science monitor : international medical journal of experimental and clinical research},
BACKGROUND Toxoplasma is an important source of foodborne hospitalization with no safe and effective therapy against chronic or congenital Toxopalsmosis. Atovaquone is a drug of choice but not approved for use in congenital Toxoplasmosis. We hypothesized atovaquone to be safe and effective against feto-maternal Toxoplasmosis. MATERIAL/METHODS Programmed pregnant mice were i.p. infected with 50-2400 Tachyzoites from Type II strain (clone PTG). Dams were treated daily with atovaquone or sham… CONTINUE READING


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2 Excerpts

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