Atorvastatin treatment improves endothelial function through endothelial progenitor cells mobilization in ischemic heart failure patients.

@article{Oikonomou2015AtorvastatinTI,
  title={Atorvastatin treatment improves endothelial function through endothelial progenitor cells mobilization in ischemic heart failure patients.},
  author={Evangelos Oikonomou and Gerasimos Siasos and Marina Zaromitidou and George Hatzis and Konstantinos Mourouzis and Christina A Chrysohoou and Konstantinos Zisimos and Savvas Mazaris and Panagiotis Tourikis and Dimitris Athanasiou and Christodoulos Stefanadis and Athanasios G. Papavassiliou and Dimitris Tousoulis},
  journal={Atherosclerosis},
  year={2015},
  volume={238 2},
  pages={159-64}
}
OBJECTIVE Endothelial function is an independent predictor of prognosis in heart failure (HF) subjects. Statins, beyond their lipid lowering role, exert beneficial effect in patients with atherosclerosis. In the present study we examined the impact of low and intermediate dose atorvastatin treatment on endothelial function, bone marrow-derived endothelial progenitor cells (EPC) mobilization and inflammatory status according to HF patient status. METHODS We studied the effect of 4 weeks… CONTINUE READING