Atorvastatin therapy improves endothelial-dependent vasodilation in patients with systemic lupus erythematosus: an 8 weeks controlled trial.

@article{Ferreira2007AtorvastatinTI,
  title={Atorvastatin therapy improves endothelial-dependent vasodilation in patients with systemic lupus erythematosus: an 8 weeks controlled trial.},
  author={Gilda Aparecida Ferreira and T{\'u}lio Pinho Navarro and R W Telles and L E Coelho Andrade and Em{\'i}lia Inoue Sato},
  journal={Rheumatology},
  year={2007},
  volume={46 10},
  pages={1560-5}
}
INTRODUCTION Patients with systemic lupus erythematosus (SLE) have recognized reduction in endothelium-dependent vasodilation. Evidence demonstrates that statins are able to improve endothelial function independently on their hypolipemic action. OBJECTIVES To evaluate the efficacy of atorvastatin in improving vasodilation in SLE patients with and without conventional risk factors for coronary heart disease (CHD). PATIENTS AND METHODS Sixty-four SLE women, mean age 31 +/- 8 yrs, received… CONTINUE READING