Atorvastatin reduces cardiac and adipose tissue inflammation in rats with metabolic syndrome.

@article{Yamada2017AtorvastatinRC,
  title={Atorvastatin reduces cardiac and adipose tissue inflammation in rats with metabolic syndrome.},
  author={Yuichiro Yamada and Shino Takeuchi and Mamoru Yoneda and S. Ito and Y. Sano and K. Nagasawa and N. Matsuura and A. Uchinaka and T. Murohara and K. Nagata},
  journal={International journal of cardiology},
  year={2017},
  volume={240},
  pages={
          332-338
        }
}
BACKGROUND Statins are strong inhibitors of cholesterol biosynthesis and help to prevent cardiovascular disease. They also exert additional pleiotropic effects that include an anti-inflammatory action and are independent of cholesterol, but the molecular mechanisms underlying these additional effects have remained unclear. We have now examined the effects of atorvastatin on cardiac and adipose tissue inflammation in DahlS.Z-Leprfa/Leprfa (DS/obese) rats, which we previously established as a… Expand
Monotherapy of experimental metabolic syndrome: I. Efficacy and safety
Rodent models of obesity.
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References

SHOWING 1-10 OF 71 REFERENCES
Effects of pioglitazone on cardiac and adipose tissue pathology in rats with metabolic syndrome.
Anti-inflammatory effect of atorvastatin ameliorates insulin resistance in monosodium glutamate-treated obese mice.
Monotherapy of experimental metabolic syndrome: I. Efficacy and safety
The ischemic heart: starving to stimulate the adiponectin-AMPK signaling axis.
Atorvastatin induces insulin sensitization in Zucker lean and fatty rats.
Atorvastatin May Delay Cardiac Aging by Upregulating Peroxisome Proliferator-Activated Receptors in Rats
...
1
2
3
4
5
...