Atorvastatin and quinapril inhibit blood coagulation in patients with coronary artery disease following 28 days of therapy.

@article{Undas2006AtorvastatinAQ,
  title={Atorvastatin and quinapril inhibit blood coagulation in patients with coronary artery disease following 28 days of therapy.},
  author={Anetta Undas and Kathleen E. Brummel-Ziedins and Daniel Piotr Potaczek and B Stobierska-Dzierzek and Leszek Bryniarski and Andrzej Szczeklik and Kenneth G. Mann},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2006},
  volume={4 11},
  pages={2397-404}
}
BACKGROUND We evaluated the antithrombotic effects of statins and angiotensin-converting enzyme inhibitor (ACEI) drugs in patients with coronary artery disease (CAD). METHODS AND RESULTS Blood coagulation at the site of microvascular injury was assessed in 26 males with CAD before and after treatment with quinapril (10 mg day-1; n=13) or atorvastatin (40 mg day-1; n=13) for 4 weeks and an additional 4 weeks of combined therapy (quinapril+atorvastatin). Rates of prothrombin and factor V… CONTINUE READING