Atorvastatin Decreases Bone Loss, Inflammation and Oxidative Stress in Experimental Periodontitis

Abstract

The aim of this study is to determine the effects of Atorvastatin treatment, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, in periodontal disease. Male Wistar albino rats were randomly divided into five groups of ten rats each: (1) non-ligated treatment (NL), (2) ligature only (L), (3) ligature plus 1 mg/kg Atorvastatin daily… (More)
DOI: 10.1371/journal.pone.0075322

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