Atopic phenotype is an important determinant of immunoglobulin E-mediated inflammation and expression of T helper cell type 2 cytokines to ascaris antigens in children exposed to ascariasis.

@article{Cooper2004AtopicPI,
  title={Atopic phenotype is an important determinant of immunoglobulin E-mediated inflammation and expression of T helper cell type 2 cytokines to ascaris antigens in children exposed to ascariasis.},
  author={Philip Cooper and Martha E. Chico and Carlos Sandoval and Thomas B Nutman},
  journal={The Journal of infectious diseases},
  year={2004},
  volume={190 7},
  pages={1338-46}
}
Studies have shown a strong inverse relationship between atopy and geohelminth infection, indicating that atopy may protect against geohelminth infection. Resistance to ascariasis in atopic individuals may occur through greater immunoglobulin E-mediated responses and expression of T helper cell type 2 (Th2) cytokines to parasite antigens. To investigate the effect that atopy has on the immune response to Ascaris antigens, school-age children were recruited from rural schools in Ecuador… CONTINUE READING
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Plasma tryptase, a marker of mast cell degranulation, is associated with the development of adverse reactions following the treatment of onchocerciasis with ivermectin

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  • 2002
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