Atomistic description of the folding of a dimeric protein.

  title={Atomistic description of the folding of a dimeric protein.},
  author={Stefano Piana and Kresten Lindorff-Larsen and David E. Shaw},
  journal={The journal of physical chemistry. B},
  volume={117 42},
Equilibrium molecular dynamics simulations are increasingly being used to describe the folding of individual proteins and protein domains at an atomic level of detail. Isolated protein domains, however, are rarely observed in vivo, where multidomain proteins and multimeric assemblies are far more common. It is clear that the folding of such proteins is… CONTINUE READING