Atomic structure of a Na+- and K+-conducting channel

@article{Shi2006AtomicSO,
  title={Atomic structure of a Na+- and K+-conducting channel},
  author={Ning Shi and Sheng Ye and Amer Alam and Liping Chen and Youxing Jiang},
  journal={Nature},
  year={2006},
  volume={440},
  pages={570-574}
}
Ion selectivity is one of the basic properties that define an ion channel. Most tetrameric cation channels, which include the K+, Ca2+, Na+ and cyclic nucleotide-gated channels, probably share a similar overall architecture in their ion-conduction pore, but the structural details that determine ion selection are different. Although K+ channel selectivity has been well studied from a structural perspective, little is known about the structure of other cation channels. Here we present crystal… Expand
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