Atomic structure of a Na+- and K+-conducting channel

  title={Atomic structure of a Na+- and K+-conducting channel},
  author={N. Shi and S. Ye and A. Alam and L. Chen and Y. Jiang},
  • N. Shi, S. Ye, +2 authors Y. Jiang
  • Published 2006
  • Chemistry, Medicine
  • Nature
  • Ion selectivity is one of the basic properties that define an ion channel. Most tetrameric cation channels, which include the K+, Ca2+, Na+ and cyclic nucleotide-gated channels, probably share a similar overall architecture in their ion-conduction pore, but the structural details that determine ion selection are different. Although K+ channel selectivity has been well studied from a structural perspective, little is known about the structure of other cation channels. Here we present crystal… CONTINUE READING
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