Atomic force microscopy studies of living cells: visualization of motility, division, aggregation, transformation, and apoptosis.

Abstract

Atomic force microscopy, in contact mode, has been used to image living mammalian cells in culture at both low and high resolutions. The method is shown practical for revealing cytoskeletal features beneath the cell membrane and their restructuring during a variety of cellular activities. Among the processes that we have visualized are locomotion, tissue… (More)

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