Atomic force microscopy studies of functional and dysfunctional pulmonary surfactant films. I. Micro- and nanostructures of functional pulmonary surfactant films and the effect of SP-A.

@article{Zuo2008AtomicFM,
  title={Atomic force microscopy studies of functional and dysfunctional pulmonary surfactant films. I. Micro- and nanostructures of functional pulmonary surfactant films and the effect of SP-A.},
  author={Yi Y Zuo and Eleonora Keating and Lin Shuang Zhao and Seyed M Tadayyon and Ruud A. W. Veldhuizen and Nils O. Petersen and Fred Possmayer},
  journal={Biophysical journal},
  year={2008},
  volume={94 9},
  pages={3549-64}
}
Monolayers of a functional pulmonary surfactant (PS) can reach very low surface tensions well below their equilibrium value. The mechanism by which PS monolayers reach such low surface tensions and maintain film stability remains unknown. As shown previously by fluorescence microscopy, phospholipid phase transition and separation seem to be important for… CONTINUE READING