Atomic force microscopy of biological membranes.

@article{Frederix2009AtomicFM,
  title={Atomic force microscopy of biological membranes.},
  author={Patrick L Frederix and Patrick Dominic Bosshart and Andreas K. Engel},
  journal={Biophysical journal},
  year={2009},
  volume={96 2},
  pages={
          329-38
        }
}
Atomic force microscopy (AFM) is an ideal method to study the surface topography of biological membranes. It allows membranes that are adsorbed to flat solid supports to be raster-scanned in physiological solutions with an atomically sharp tip. Therefore, AFM is capable of observing biological molecular machines at work. In addition, the tip can be tethered to the end of a single membrane protein, and forces acting on the tip upon its retraction indicate barriers that occur during the process… CONTINUE READING
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