Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative

@article{Kawaura1998AtomicFM,
  title={Atomic force microscopy for studying gene transfection mediated by cationic liposomes with a cationic cholesterol derivative},
  author={Chiyo Kawaura and Ari Noguchi and Tadahide Furuno and Mamoru Nakanishi},
  journal={FEBS Letters},
  year={1998},
  volume={421}
}
Atomic force microscopy (AFM) was used for studying gene transfection mediated by cationic liposomes which contain a cationic cholesterol derivative with a different spacer arm. Cationic liposomes were made by a mixture of one of eight cationic cholesterol derivatives and 1,2‐dioleoyl‐sn‐glycero‐3‐phosphatidyl ethanolamine (DOPE). AFM images showed that vesicles made of the liposome/DNA complex had various diameters depending on each cationic cholesterol derivative with a different spacer arm… 
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