Atomic force microscopy-based force spectroscopy--biological and biomedical applications.

@article{Carvalho2012AtomicFM,
  title={Atomic force microscopy-based force spectroscopy--biological and biomedical applications.},
  author={Filomena A Carvalho and Nuno Miguel Carvalho Santos},
  journal={IUBMB life},
  year={2012},
  volume={64 6},
  pages={
          465-72
        }
}
The use of atomic force microscopy (AFM) applied to biological systems to generate high resolution images is gaining a wider acceptance. However, the most remarkable advances are being achieved on the use of the AFM to measure inter- and intramolecular interaction forces with piconewton resolution, not only to demonstrate this ability but also actually to solve biological and biomedical relevant questions. Single-molecule force spectroscopy recognition studies enable the detection of specific… CONTINUE READING
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