Atomic force microscopy analysis and confocal Raman microimaging of coated pellets.

  title={Atomic force microscopy analysis and confocal Raman microimaging of coated pellets.},
  author={Ann Ringqvist and L. Taylor and K. Ekelund and G. Ragnarsson and S. Engstr{\"o}m and A. Axelsson},
  journal={International journal of pharmaceutics},
  volume={267 1-2},
  • Ann Ringqvist, L. Taylor, +3 authors A. Axelsson
  • Published 2003
  • Chemistry, Medicine
  • International journal of pharmaceutics
  • Polymer-coated pellets with different coating thicknesses have been studied regarding coating morphology and drug release properties with atomic force microscopy (AFM) and confocal Raman microscopy. The results were compared with those from scanning electron microscopy (SEM) and drug release profiles, which have been measured previously for these systems and found to vary depending on coating thickness. Results from AFM studies indicated that these pellets differ in the amount of crystalline… CONTINUE READING
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