Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles

@article{Yuana2010AtomicFM,
  title={Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles},
  author={Yuana Yuana and Tjerk H Oosterkamp and Svetlana Bahatyrova and Brian Ashcroft and P Garcia Rodriguez and Rogier M. Bertina and Susanne Osanto},
  journal={Journal of Thrombosis and Haemostasis},
  year={2010},
  volume={8}
}
See also Freyssinet J‐M, Toti F. Membrane microparticle determination: at least seeing what’s being sized! This issue, pp 311–4. 
Membrane microparticle determination: at least seeing what’s being sized!
TLDR
Atomic force microscopy: a novel approach to the detection of nanosized blood microparticles and its applications in medicine and materials science. Expand
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References

SHOWING 1-10 OF 30 REFERENCES
Membrane microparticles: two sides of the coin.
Microparticles are plasma membrane-derived vesicles shed from stimulated cells, in the broad sense of the term. Their presence is interpreted by proximal or remote cells in fundamental physiologicalExpand
Adsorption of biological molecules to a solid support for scanning probe microscopy.
TLDR
The commonly used method of adsorbing biological specimens to freshly cleaved mica is analysed, facilitated by adjusting the electrolyte concentration and the pH of the buffer solution. Expand
Platelet-derived microparticles on synthetic surfaces observed by atomic force microscopy and fluorescence microscopy.
TLDR
A quantitative investigation on the production and dimensions of platelet-derived microparticles observed on glass and polyethylene under aqueous conditions, using atomic force microscopy (AFM) and complementary fluorescence microscopy shows that contact-activated plateletmicroparticles are not evenly distributed over a thrombogenic surface, but in clusters in close proximity to adherent platelets. Expand
From molecules to cells: imaging soft samples with the atomic force microscope.
TLDR
An overview is presented on the application of atomic force microscopy to organic samples ranging from thin ordered films at molecular resolution to living cells and novel imaging modes are introduced that exploit different aspects of the tip-sample interaction for local measurements of the micromechanical properties of the sample. Expand
Detection and measurement of microparticles: an evolving research tool for vascular biology.
TLDR
It now appears that all circulating blood cells as well as endothelial cells release membranous fragments ~1 mum in size or smaller bearing at least some characteristics of the parent cell. Expand
Past, present and future of atomic force microscopy in life sciences and medicine
TLDR
Recent progress made using AFM for studying cells and cellular interactions, probing single molecules, imaging biosurfaces at high resolution and investigating model membranes and their interactions are presented. Expand
Standardization of platelet‐derived microparticle counting using calibrated beads and a Cytomics FC500 routine flow cytometer: a first step towards multicenter studies?
TLDR
This calibrated‐bead strategy allowed full long‐term control of the FCM‐based microparticle protocol and reproducible PMP counts over time and opens the way for multicenter studies. Expand
ADSORPTION OF BIOMOLECULES ON TITANIUM OXIDE LAYERS IN BIOLOGICAL MODEL SOLUTIONS
This thesis deals with the interactions of biomolecules, mainly proteins, on TiO2 and some other selected surfaces found on implants. The main focus lies in the kinetics of the adsorption processesExpand
Tissue factor-bearing microparticles and cancer.
  • J. Zwicker
  • Medicine
  • Seminars in thrombosis and hemostasis
  • 2008
TLDR
This work is using an impedance-based flow cytometer to accurately size and enumerate TF-bearing microparticles to explore the association between cancer thrombosis and elevations in circulating TF- Bearing Microparticles. Expand
Cell-derived microparticles in haemostasis and vascular medicine.
TLDR
The literature regarding microparticles in their widest definition, including ectosomes and exosomes, are reviewed, to focus mainly on their role in haemostasis and vascular medicine. Expand
...
1
2
3
...