Atomic force microscope infrared spectroscopy of griseofulvin nanocrystals.

Abstract

The goal of this work was to evaluate the ability of photothermal-induced resonance (PTIR) to measure the local infrared absorption spectra of crystalline organic drug nanoparticles embedded within solid matrices. Herein, the first reports of the chemical characterization of sub-100 nm organic crystals are described; infrared spectra of 90 nm griseofulvin… (More)
DOI: 10.1021/ac4025889

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