Atmospheric-pressure ionization and fragmentation of peptides by solution-cathode glow discharge.

@article{Schwartz2016AtmosphericpressureIA,
  title={Atmospheric-pressure ionization and fragmentation of peptides by solution-cathode glow discharge.},
  author={Andrew J Schwartz and Jacob T. Shelley and Courtney L. Walton and Kelsey L. Williams and Gary M. Hieftje},
  journal={Chemical science},
  year={2016},
  volume={7 10},
  pages={6440-6449}
}
Modern "-omics" (e.g., proteomics, glycomics, metabolomics, etc.) analyses rely heavily on electrospray ionization and tandem mass spectrometry to determine the structural identity of target species. Unfortunately, these methods are limited to specialized mass spectrometry instrumentation. Here, a novel approach is described that enables ionization and… CONTINUE READING